The Instrumentally Derived Incentive-Motivational Function

Hot or Not: Response Inhibition Reduces the Hedonic Value and Motivational Incentive of Sexual Stimuli

The motivational incentive of reward-related stimuli can become so salient that it drives behavior at the cost of other needs. Here we show that response inhibition applied during a Go/No-go task not only impacts hedonic evaluations but also reduces the behavioral incentive of motivationally relevant stimuli. We first examined the impact of response inhibition on the hedonic value of sex stimul...

Dopamine gating of glutamatergic sensorimotor and incentive motivational input signals to the striatum.

Dopamine (DA) neurons of the substantia nigra (SN) and ventral tegmental area (VTA) respond to a wide category of salient stimuli. Activation of SN and VTA DA neurons, and consequent release of nigrostriatal and mesolimbic DA, modulates the processing of concurrent glutamate inputs to dorsal and ventral striatal target regions. According to the view described here, this occurs under conditions ...

The Effects of a Central Incentive - Motivational State on Measures of Job Satisfaction

Subthalamic nucleus lesions enhance the psychomotor-activating, incentive motivational, and neurobiological effects of cocaine.

The subthalamic nucleus (STN) is traditionally thought to be involved in motor control, and dysfunction of the STN is thought to contribute to movement disorders. Here, we show that the STN also plays an important role in motivational processes and the response to drugs of abuse. Specifically, bilateral STN lesions produced a dose-dependent increase in the psychomotor-activating effects of coca...

Effect of Incentive Spirometry on Pulmonary Function Tests in Patients Undergoing Hemodialysis: A Randomized Clinical Trials

Objectives: This study was aimed to determine the Effect effect of incentive spirometry on pulmonary function tests in patients undergoing hemodialysis. Methods: This study was a randomized clinical trial conducted in on hemodialysis patients. The obtained Data were collected from 26 patients in the experimental and 26 patients in the control group. In The the control group, patients received ...